Innovative DNA Array Technology Detection of Pharmaceuticals Reclaimed Water

WERF Report 01-HHE-21T

Currency:

Standard price: £29.00

Available as an ebook

Please purchase via www.iwaponline.comOpens in new window

Also part of Water Intelligence Online Digital Reference Library

Standard ePrice: £29.00

+ VAT

Access ebook

Author(s): SW Kullman

Publication Date: 30/04/2007

Pages: 80

Binding: Paperback

ISBN13: 9781843397373

eISBN: 9781780403861

Download book flyer Print page

Numerous pharmaceutical substances and their metabolites have been identified in the aquatic environment. Due to their unique environmental fate and lack of appropriate biomonitoring techniques, the potential risk of these compounds to public and environmental health has largely been undetermined.

Recent interest in quantifying pharmaceuticals in waste effluents and aquatic environments has identified the need to develop bioanalytical assays that will accurately reflect presence of these compounds.

The goal of this research was to investigate the use of DNA microarrays as a bioanalytical tool for analysis of pharmaceutical contamination in re-use waters. Results from this study suggest that prototypic pharmaceutical contaminants target molecular events associated with pharmaceutical-induced gene induction and repression in exposed organisms.

Gene expression profiles are subsequently evaluated as a means to discern pharmaceutical exposure. When fully developed, this bioanalytical approach will provide an efficient and robust method for screening pharmaceutical contaminants in reuse and other water matrices. 

SW Kullman

The latest from @IWApublishing

RT : Are you interested in contributing to the Special Issue on ? https://t.co/m2OmOxUWN2 2 days 14 hours ago
"Propagation dynamics and causes of hydrological in response to drought at seasonal timesc… https://t.co/ZIP4CXiUBM 4 days 14 hours ago
RT : 🚨Not long left to submit your paper for peer review and possible publication in this Special Issue ⬇ Relevant topi… https://t.co/M1bVqyuUIw 4 days 14 hours ago